Results tagged “eczema” from Allergy

Researchers have long noted that many asthma sufferers also have atopic dermatitis -- often called eczema -- a chronic disease of the skin that can leave it red, raw, scaly, tender, oozy and excruciatingly itchy. But scientists are looking at whether such ravaging of the skin creates the conditions that can trigger asthma.

British scientists reported last spring in the journal Nature Genetics that people who suffer from both eczema and asthma carry the same gene mutation and concluded that in some cases eczema may actually lead to asthma.

Researchers have long noted that many asthma sufferers also have atopic dermatitis — often called eczema — a chronic disease of the skin that can leave it red, raw, scaly, tender, oozy and excruciatingly itchy. But scientists are looking at whether such ravaging of the skin creates the conditions that can trigger asthma.

Last spring in the journal Nature Genetics, British scientists reported that people who suffer from both eczema and asthma carry the same gene mutation and concluded that eczema may actually lead to asthma in some cases.

Until now, it had largely been assumed that dander, dust mites, pollen and other allergens that can cause asthma enter the body through the respiratory system. But the researchers said they now believe that they can also enter the body through tiny breaks in the skin’s surface — something that occurs in patients with eczema.

Background: Maternal diet during pregnancy might be one of the factors that influences fetal immune responses associated with childhood allergy.

Objective: We analyzed the association between maternal diet during the last 4 wk of pregnancy and allergic sensitization and eczema in the offspring at 2 y of age.

Design: Data from 2641 children at 2 y of age were analyzed within a German prospective birth cohort study (LISA). Maternal diet during the last 4 wk of pregnancy was assessed with a semiquantitative food-frequency questionnaire, which was administered shortly after childbirth.

Gut parasites could hold the key to increasingly common conditions such as eczema, asthma and hay fever, according to scientists at The University of Nottingham.

Gut parasites, such as hookworm, have evolved together with their human hosts for millions of years. Over time, these parasites have developed ways of surviving in the human gut by 'turning down' the immune response directed against them, prolonging their survival inside the host.

This reduction in immune response may also have the effect of reducing allergic tissue reactions that characterise asthma and other allergic conditions.

On Saturday, October 7, 2006, the AAP Section on Allergy and Immunology sponsored a session reviewing recent publications in the fields of asthma, eczema, and urticaria.

Asthma Diagnosis and Management

The first speaker was Dr. Paul Williams, Northwest Asthma and Allergy Center in Seattle, Washington, who was Chairman of the Section on Allergy and Immunology at AAP. He highlighted recent articles on the prevention of and care for patients with asthma. He reviewed studies covering the epidemiology of asthma, identification of severity and proper severity classification, and variation in symptom severity.^[1]

Background: Patients with hand eczema frequently have a history of atopic dermatitis or atopy. No specific morphologic pattern of hand eczema helps distinguish atopic hand eczema from other etiologies. There are few studies of hand eczema prevalence and morphology in a well-defined population of patients with atopic dermatitis.

Methods: We evaluated 777 consecutive patients with atopic dermatitis (diagnosed by standard criteria) for hand involvement. An additional 100 patients had further evaluations, including evaluation of the historical and morphologic characteristics of their hand eczema.

The body's mast cells are mainly associated with allergic reaction in the way they release histamine and other inflammatory substances. However, researchers at Karolinska Institutet have now demonstrated how the mast cells can also contribute to diseases like psoriasis and cancer.

Mast cells are most known for their association with allergic reactions, as they act like microscopic "bombs" to trigger the release of a number of substances that give rise to the classic allergic symptoms, such as swelling, congestion and itching. The explosive reactions are activated when an allergen (such as pollen particles) binds to receptors on the surface of the mast cell, which then opens and secretes part of its contents.